Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPIF | P30405 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568477 | 0.83 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL8563296 | 0.80 | ALDH1A1 (0.51) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL8566453 | 0.80 | MEN1 (0.58) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL8568512 | 0.79 | CA1 (0.41) | KMT2AMEN1NPC1ARCA1 | |
| SCHEMBL8629441 | 0.78 | ALDH1A1 (0.39) | KMT2AMEN1NPC1RAB9ACA1 | |
| SCHEMBL8563598 | 0.77 | LMNA (0.55) | KMT2AATMCA9KDM4EALDH1A1 | |
| SCHEMBL4619784 | 0.77 | KMT2A (0.84) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL8625161 | 0.76 | CYP19A1 (0.39) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL8567103 | 0.75 | MGMT (0.50) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL8559976 | 0.74 | AR (0.44) | KMT2AMEN1NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |