Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563864 | 0.83 | NSD2 (0.49) | LMNACYP19A1KDM4ENSD2CA12 | |
| SCHEMBL8563126 | 0.80 | CYP19A1 (0.50) | LMNACYP19A1NSD2CA12CA9 | |
| SCHEMBL8563296 | 0.79 | ALDH1A1 (0.51) | LMNAKDM4EKMT2AALDH1A1MAPK1 | |
| SCHEMBL4504076 | 0.79 | CYP19A1 (0.83) | LMNACYP19A1CA12CA9VCAM1 | |
| SCHEMBL8597357 | 0.78 | ALDH1A1 (0.39) | LMNACYP19A1KDM4ECA12KMT2A | |
| SCHEMBL8567910 | 0.78 | RAB9A (0.58) | LMNACYP19A1KDM4ECA12CA9 | |
| SCHEMBL8566147 | 0.77 | KMT2A (0.53) | CYP19A1KDM4ECA9KMT2AALDH1A1 | |
| SCHEMBL8599314 | 0.76 | RECQL (0.51) | LMNAKDM4ECA12CA9KMT2A | |
| SCHEMBL8561895 | 0.75 | HTT (0.52) | LMNACYP19A1KDM4ENSD2CA12 | |
| SCHEMBL8560152 | 0.75 | CYP19A1 (0.60) | LMNACYP19A1CA12VCAM1SLC12A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |