SCHEMBL8566474

SCHEMBL8566474

CNCCN1CCN(CCNC)C(C)(C)C1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 11/20 0.47
PRMT6 Q96LA8 11/20 0.47
PRMT8 Q9NR22 2/20 0.47
PRMT1 Q99873 1/20 0.41
SLC29A1 Q99808 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801597 0.74 HTR1A (0.36) SLC29A1
SCHEMBL240714 0.73
SCHEMBL1045046 0.73 CARM1 (0.79) CARM1PRMT6PRMT8PRMT1
SCHEMBL9801598 0.72 ALDH1A1 (0.38) SLC29A1
SCHEMBL9801620 0.72 ALOX15 (0.48) SLC29A1
SCHEMBL12478392 0.72 CARM1 (0.45) CARM1PRMT6PRMT8PRMT1
Ammonia Solution, Strong SCHEMBL28093092 0.71 CARM1 (0.43) CARM1PRMT6PRMT8PRMT1
SCHEMBL9927938 0.69
SCHEMBL9801186 0.69 SLC29A1 (0.41) SLC29A1
Ammonia Solution, Strong SCHEMBL28794902 0.69 CARM1 (0.47) CARM1PRMT6PRMT8PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2640507-B1 ACID GAS ABSORBENT COMPOSITION NALCO CO (US) 2019-05-08 EP disclosed
US-8765951-B2 Acid gas absorbent composition NALCO COMPANY (US) 2014-07-01 US disclosed
US-8765083-B2 Acid gas absorbent composition NALCO COMPANY (US) 2014-07-01 US disclosed
US-20130240782-A1 ACID GAS ABSORBENT COMPOSITION CHAMPIONX LLC 2013-09-19 US disclosed
US-20120128561-A1 ACID GAS ABSORBENT COMPOSITION US SYNTHETIC CORPORATION 2012-05-24 US disclosed