Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 7/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.35 |
| ▸ | CDK1 | P06493 | 7/20 | 0.35 |
| ▸ | CDK4 | P11802 | 7/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.35 |
| ▸ | CCND1 | P24385 | 7/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.35 |
| ▸ | CDK2 | P24941 | 7/20 | 0.35 |
| ▸ | CCND2 | P30279 | 7/20 | 0.35 |
| ▸ | CCND3 | P30281 | 7/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473276 | 0.84 | CCNB2 (0.37) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL9043636 | 0.79 | CYP2D6 (0.36) | CYP2D6CYP3A4CYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL8297105 | 0.75 | LTA4H (0.38) | CYP2D6CYP3A4CYP1A2NPC1RAB9A | |
| SCHEMBL9683149 | 0.73 | LTA4H (0.39) | CYP2D6CYP3A4CYP1A2GRIN2DGRIN3B | |
| SCHEMBL1582737 | 0.72 | ALDH1A1 (0.40) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL9047154 | 0.71 | NPC1 (0.35) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL14699864 | 0.71 | LTA4H (0.42) | CYP2D6CYP3A4CYP1A2NPC1RAB9A | |
| SCHEMBL10203437 | 0.70 | GRIN2D (0.39) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL10692851 | 0.70 | LTA4H (0.46) | CYP2D6CYP3A4CYP1A2RAB9ACYP19A1 | |
| SCHEMBL15295256 | 0.68 | L3MBTL1 (0.44) | CCNB2CCNE2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |