Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175489 | 0.88 | CTSD (0.61) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL8560511 | 0.85 | CYSLTR2 (0.63) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9181654 | 0.84 | CTSD (0.58) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9170767 | 0.77 | CTSD (0.47) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9178362 | 0.75 | CTSD (0.46) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9173547 | 0.74 | GRM2 (0.68) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL2862125 | 0.74 | MAPT (0.49) | CTSD | |
| SCHEMBL9711382 | 0.74 | CYSLTR2 (0.54) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9173919 | 0.73 | CYSLTR1 (0.64) | CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9172468 | 0.72 | LMNA (0.68) | CTSDCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |