Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770602 | 0.87 | CTSB (0.49) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9770640 | 0.73 | CTSB (0.54) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9059478 | 0.73 | CTSB (0.56) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8566829 | 0.70 | MAPT (0.43) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10683266 | 0.70 | CYP3A4 (0.41) | LMNAMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3342318 | 0.70 | TSHR (0.51) | LMNAMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1286290 | 0.70 | MAPT (0.43) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4871412 | 0.70 | CTSB (1.00) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2206983 | 0.68 | CTSB (0.68) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30779614 | 0.68 | CTSB (0.68) | CTSBLMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |