Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562255 | 0.82 | ALDH1A1 (0.51) | MGMTCA1CA2CA9RAB9A | |
| SCHEMBL8566052 | 0.79 | NSD2 (0.49) | CA1CA2CA9HTTMAPT | |
| SCHEMBL8566919 | 0.77 | MGMT (0.53) | MGMTPIN1HTTMAPTMEN1 | |
| SCHEMBL8567103 | 0.77 | MGMT (0.50) | MGMTCA1CA2CA9RAB9A | |
| SCHEMBL8559976 | 0.76 | AR (0.44) | CA1CA2CA9RAB9APIN1 | |
| SCHEMBL8630572 | 0.76 | CA12 (0.31) | CA1CA2CA9CA7 | |
| SCHEMBL8566243 | 0.76 | MGMT (0.46) | MGMTCA1CA2CA9RAB9A | |
| SCHEMBL8565798 | 0.76 | RAB9A (0.55) | MGMTRAB9AMAPTKMT2ALMNA | |
| SCHEMBL8626079 | 0.74 | CA2 (0.37) | CA1CA2CA9RAB9AMAPT | |
| SCHEMBL8562212 | 0.73 | PIN1 (0.46) | MGMTCA1CA2CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |