Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614546 | 0.74 | ALDH1A1 (0.44) | LMNAKDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL17294176 | 0.73 | ALDH1A1 (0.43) | LMNAKDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL3487989 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1427035 | 0.69 | LMNA (0.37) | LMNAADORA3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1426445 | 0.69 | F2 (0.39) | LMNAADORA3ALDH1A1F2ELANE | |
| SCHEMBL1426485 | 0.67 | LMNA (0.41) | LMNAADORA3KDM4EALDH1A1F2 | |
| SCHEMBL6381411 | 0.66 | LMNA (0.42) | LMNAKDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL20416267 | 0.65 | IDO1 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL17294174 | 0.65 | — | — | |
| SCHEMBL4661522 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843396-A | Method for stabilizing radiolabeled organic compounds by adding a separate stabilizing compound | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| US-5738836-A | Composition for stabilizing radiolabeled organic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-4411881-A | Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines | NEW ENGLAND NUCLEAR CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |