Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263274 | 0.82 | NPSR1 (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9800779 | 0.73 | MEN1 (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL1732991 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL8566934 | 0.72 | LMNA (0.32) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL2376039 | 0.69 | HSD17B10 (0.39) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL17536132 | 0.67 | HSD17B10 (0.38) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL19918261 | 0.64 | KDM4E (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10730263 | 0.64 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11771044 | 0.61 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAPOLBIDH1 | |
| SCHEMBL23595456 | 0.61 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062984-A1 | FGF-23 POLYPEPTIDES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2010-03-11 | — | — | US | disclosed |
| WO-2008092019-A1 | FGF-23 POLYPEPTIDES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-07-31 | — | — | WO | disclosed |