Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544542 | 0.81 | HTT (0.33) | HPGD | |
| SCHEMBL22183998 | 0.79 | HPGD (0.32) | HPGD | |
| SCHEMBL2258516 | 0.77 | HPGD (0.34) | HPGD | |
| SCHEMBL5089366 | 0.77 | HPGD (0.31) | HPGD | |
| SCHEMBL10779530 | 0.76 | CES2 (0.42) | — | |
| SCHEMBL9100028 | 0.76 | LMNA (0.37) | HPGD | |
| SCHEMBL2993973 | 0.76 | — | — | |
| SCHEMBL28707291 | 0.74 | USP2 (0.32) | HPGD | |
| SCHEMBL15375841 | 0.74 | — | — | |
| SCHEMBL30064 | 0.74 | ACHE (0.42) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866793-A4 | — | — | 1998-10-07 | — | — | EP | disclosed |
| EP-0866793-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997001562-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |