Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL8566793 | 0.94 | ALDH1A1 (0.39) | CSNK1DMAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8567357 | 0.87 | ALDH1A1 (0.38) | CSNK1DMAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8568227 | 0.80 | ALDH1A1 (0.39) | CSNK1DMAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8562572 | 0.79 | ALDH1A1 (0.38) | CSNK1DSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL8567515 | 0.79 | VCP (0.41) | SMN1; SMN2ALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL9050612 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8563542 | 0.76 | ALDH1A1 (0.39) | MAPTSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL8560120 | 0.69 | ALDH1A1 (0.38) | MAPTSMN1; SMN2ALDH1A1TDP1KMT2A | |
| SCHEMBL10004802 | 0.69 | KMT2A (0.44) | CSNK1DMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9051616 | 0.68 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552060-B1 | Imidazole derivatives having anti-HIV activity | SHIONOGI & CO (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0700911-A1 | Imidazole derivatives having anti-HIV activity | SHIONOGI & CO., LTD. (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5472965-A | Useful for treatment of retrovirus infections; less toxic | SHIONOGI & CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| US-5326780-A | Acquired immunodeficiency syndrome | SHIONOGI & CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0552060-A1 | Imidazole derivatives having anti-HIV activity | SHIONOGI & CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |