Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411938 | 0.80 | RAB9A (0.57) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28704926 | 0.77 | RAB9A (0.48) | NPC1RAB9AMEN1KMT2ADDX3X | |
| SCHEMBL4403796 | 0.75 | RAB9A (0.56) | RAB9ATRPV1USP2TSHR | |
| SCHEMBL26717815 | 0.74 | TRPV1 (0.56) | RAB9ATRPV1USP2TSHR | |
| SCHEMBL4404394 | 0.74 | TRPV1 (0.56) | RAB9ATRPV1USP2TSHR | |
| SCHEMBL25787257 | 0.72 | DDX3X (0.55) | NPC1RAB9AMEN1KMT2ADDX3X | |
| SCHEMBL25808664 | 0.71 | RAB9A (0.43) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL17978449 | 0.71 | LMNA (0.71) | NPC1RAB9AKMT2ADDX3XTRPV1 | |
| SCHEMBL4405209 | 0.70 | TOP2A (0.40) | NPC1RAB9AMEN1KMT2AGRM2 | |
| SCHEMBL9210936 | 0.70 | MAPT (0.40) | NPC1RAB9AMEN1KMT2ADDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846117-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040684-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |