Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | HRH1 | P35367 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947463 | 0.78 | HRH3 (0.61) | HRH3HRH1MAPTHRH2KDM4E | |
| SCHEMBL9270379 | 0.74 | FFAR1 (0.64) | MAPTALDH1A1KDM4EHPGDFFAR1 | |
| SCHEMBL2981970 | 0.73 | HRH3 (0.64) | HRH3HRH1HRH2DRD2HTR2A | |
| SCHEMBL7954928 | 0.73 | HRH1 (0.61) | HRH3HRH1MAPTALDH1A1HRH2 | |
| SCHEMBL23657631 | 0.72 | TDP1 (0.49) | MAPTALDH1A1HPGDFFAR1TSHR | |
| SCHEMBL27462633 | 0.72 | HRH3 (0.49) | HRH3HRH1MAPTHRH2TSHR | |
| SCHEMBL7956560 | 0.71 | KDM4E (0.65) | HRH3HRH1KDM4EJAK2 | |
| SCHEMBL920681 | 0.70 | FFAR1 (0.56) | ALDH1A1KDM4EHPGDFFAR1MAOB | |
| SCHEMBL7958205 | 0.69 | F10 (0.53) | HRH3HRH1MAPTHRH2FFAR1 | |
| SCHEMBL9778462 | 0.69 | KCNH2 (0.52) | ALDH1A1HTR2AKDM4EHPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880501-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028128-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |