Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 2/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563215 | 0.88 | KMT2A (0.42) | NAPRTALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL8561844 | 0.86 | MAPT (0.41) | NAPRTALDH1A1MAPTKDM4EHTT | |
| SCHEMBL8562600 | 0.81 | LMNA (0.47) | ALDH1A1MAPTKDM4EHTTMITF | |
| SCHEMBL31693360 | 0.80 | ASPH (0.55) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL27888702 | 0.80 | KDM4E (0.43) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL15758083 | 0.80 | ASPH (0.55) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL8570524 | 0.80 | MAPT (0.42) | NAPRTCYP3A4MAPTKDM4EHTT | |
| SCHEMBL2747912 | 0.79 | TSHR (0.45) | ALDH1A1TDP1MAPTKDM4EASPH | |
| SCHEMBL31092297 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL2747917 | 0.79 | TSHR (0.45) | ALDH1A1TDP1MAPTKDM4EASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |