Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567191 | 0.86 | NAPRT (0.50) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL8563215 | 0.85 | KMT2A (0.42) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL30590420 | 0.81 | KMT2A (0.38) | MAPTLMNASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL8597037 | 0.77 | FAAH (0.41) | MAPTHTTLMNAKMT2AALDH1A1 | |
| SCHEMBL8563829 | 0.77 | MAPK1 (0.37) | MAPTHTTKDM4EKMT2AMAPK1 | |
| SCHEMBL8565505 | 0.75 | MAPT (0.45) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL204345 | 0.75 | NOS2 (0.50) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL29674727 | 0.75 | NOS2 (0.50) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL8562600 | 0.75 | LMNA (0.47) | MAPTHTTKDM4EMITFLMNA | |
| SCHEMBL30898769 | 0.74 | NOS3 (0.48) | SMN1; SMN2ALDH1A1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |