Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564862 | 0.80 | KDM4E (0.37) | MAPTLMNAHTTKDM4EMEN1 | |
| SCHEMBL8567191 | 0.80 | NAPRT (0.50) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8565828 | 0.77 | MAPT (0.39) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8563215 | 0.75 | KMT2A (0.42) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8562600 | 0.75 | LMNA (0.47) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8568617 | 0.74 | MAPK1 (0.38) | MAPTSMN1; SMN2LMNAHTTCDK5 | |
| SCHEMBL8561844 | 0.74 | MAPT (0.41) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL18131091 | 0.72 | MDM2 (0.49) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8562423 | 0.72 | RAB9A (0.52) | MAPTLMNAHTTKDM4EMGMT | |
| SCHEMBL8568952 | 0.72 | HTT (0.52) | MAPTLMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |