Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561287 | 0.82 | POLB (0.42) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8566311 | 0.82 | MGMT (0.61) | MGMTPIN1ELANELMNAMAPT | |
| SCHEMBL8597821 | 0.81 | LMNA (0.43) | KMT2AMEN1LMNAATMMAPT | |
| SCHEMBL8563611 | 0.80 | PIN1 (0.54) | MGMTPIN1ELANEKMT2AMEN1 | |
| SCHEMBL8559235 | 0.78 | KDM4E (0.41) | ELANEKMT2AMEN1LMNANPC1 | |
| SCHEMBL8563863 | 0.78 | ALDH1A1 (0.51) | MGMTKMT2AMEN1LMNARAB9A | |
| SCHEMBL8922116 | 0.78 | MGMT (0.39) | MGMTPIN1ELANEKMT2AMEN1 | |
| SCHEMBL8564625 | 0.77 | MAPT (0.38) | KMT2AMEN1LMNARAB9AMAPT | |
| SCHEMBL8565124 | 0.77 | KDM4E (0.38) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL8564523 | 0.77 | KDM4E (0.53) | ELANEKMT2AMEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |