Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624593 | 0.84 | MAPT (0.35) | KMT2AALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8565650 | 0.83 | MGMT (0.50) | MGMTCA1CA2CA9PIN1 | |
| SCHEMBL8926837 | 0.82 | LMNA (0.38) | CA2KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL8565656 | 0.81 | TXNRD1 (0.44) | CA1CA2CA9KMT2AALDH1A1 | |
| SCHEMBL8562352 | 0.79 | KDM4E (0.41) | CA1CA2CA9KMT2AALDH1A1 | |
| SCHEMBL8568326 | 0.79 | MGMT (0.44) | MGMTCA1CA2CA9PIN1 | |
| SCHEMBL8567087 | 0.79 | VCAM1 (0.46) | CA9KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8566049 | 0.78 | KDM4E (0.40) | KMT2AALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8567582 | 0.78 | MGMT (0.48) | MGMTPIN1KMT2AALDH1A1LMNA | |
| SCHEMBL8562983 | 0.77 | PIN1 (0.48) | CA1CA2CA9PIN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |