Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27933490 | 0.79 | ALDH1A1 (0.41) | HTTGAALMNAALDH1A1POLB | |
| SCHEMBL874591 | 0.78 | ALDH1A1 (0.56) | HTTGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8595791 | 0.78 | TDP1 (0.42) | HTTGAALMNAALDH1A1TXNRD1 | |
| Hydrochloric Acid SCHEMBL27949051 | 0.78 | ALDH1A1 (0.43) | HTTGAALMNAALDH1A1POLB | |
| SCHEMBL8563438 | 0.77 | RAB9A (0.50) | HTTGAALMNAALDH1A1KMT2A | |
| SCHEMBL31451941 | 0.76 | MAPT (0.42) | HTTGAALMNAALDH1A1TXNRD1 | |
| SCHEMBL8560018 | 0.75 | ALDH1A1 (0.56) | HTTGAALMNAALDH1A1POLB | |
| SCHEMBL5106496 | 0.75 | HTT (0.43) | HTTGAALMNAALDH1A1POLB | |
| SCHEMBL19172441 | 0.74 | NPC1 (0.50) | HTTGAALMNAALDH1A1KMT2A | |
| SCHEMBL8564571 | 0.73 | MAPT (0.43) | HTTLMNAALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |