Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567726 | 0.83 | CNR2 (0.41) | HNF4APTPN22PTPN6PTPN11KDM4E | |
| SCHEMBL8567961 | 0.80 | FAAH (0.47) | PTPN1PTPN6PTPN11KDM4EHIF1A | |
| SCHEMBL8566045 | 0.79 | FAAH (0.41) | PTPN22KDM4EHIF1AEPAS1EPHX2 | |
| SCHEMBL8570958 | 0.79 | HIF1A (0.38) | PTPN22KDM4EHIF1AEPAS1EPHX2 | |
| SCHEMBL8568941 | 0.78 | CNR2 (0.39) | PTPN22PTPN11KDM4EHIF1AEPAS1 | |
| SCHEMBL8568880 | 0.78 | KDM4E (0.33) | HNF4APTPN22KDM4EHIF1AEPAS1 | |
| SCHEMBL8570623 | 0.78 | RAB9A (0.38) | PTPN22KDM4EHIF1AEPAS1EPHX2 | |
| SCHEMBL8567786 | 0.77 | CNR2 (0.47) | PTPN1PTPN6PTPN11MAPTALDH1A1 | |
| SCHEMBL8572650 | 0.77 | CNR2 (0.47) | PTPN1PTPN6PTPN11MAPTALDH1A1 | |
| SCHEMBL8566872 | 0.77 | CNR2 (0.47) | PTPN1PTPN6PTPN11MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |