Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570522 | 0.84 | NPC1 (0.46) | MEN1KMT2ACD274ALDH1A1L3MBTL1 | |
| SCHEMBL8567749 | 0.75 | SMN1; SMN2 (0.54) | NPSR1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL8569641 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8572769 | 0.74 | TACR1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2TACR1 | |
| SCHEMBL8573485 | 0.74 | MEN1 (0.42) | MEN1KMT2ACD274ALDH1A1L3MBTL1 | |
| SCHEMBL8568184 | 0.71 | TACR1 (0.59) | TACR1 | |
| SCHEMBL1651653 | 0.70 | KDM4E (0.49) | NPSR1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8569426 | 0.69 | TACR1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2TACR1 | |
| SCHEMBL28201220 | 0.69 | HSD17B2 (0.51) | NPSR1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8572561 | 0.69 | TACR1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |