Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HK2 | P52789 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570513 | 0.82 | MEN1 (0.62) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7796405 | 0.76 | HPGD (0.49) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8567759 | 0.75 | NPSR1 (0.43) | SMN1; SMN2MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL17924581 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16516551 | 0.73 | LMNA (0.49) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8572766 | 0.73 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL8569633 | 0.72 | MEN1 (0.64) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7445918 | 0.72 | MEN1 (0.86) | SMN1; SMN2MEN1KMT2AALDH1A1KEAP1 | |
| SCHEMBL14052868 | 0.72 | FABP4 (0.56) | SMN1; SMN2MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL14052509 | 0.72 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |