Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567759 | 0.84 | NPSR1 (0.43) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL8569641 | 0.83 | MEN1 (0.47) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL14490115 | 0.81 | POLB (0.54) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL8573485 | 0.77 | MEN1 (0.42) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL15775269 | 0.76 | ABCB1 (0.48) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8818040 | 0.76 | LTB4R (0.42) | NPC1RAB9AL3MBTL1KMT2AGAA | |
| SCHEMBL8818195 | 0.75 | RXFP1 (0.46) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL13265349 | 0.73 | ABCB1 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2POLB | |
| SCHEMBL8570513 | 0.73 | MEN1 (0.62) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL4477977 | 0.72 | CD274 (0.50) | NPC1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |