Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | EYA2 | O00167 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097059 | 0.92 | LMNA (0.52) | TBXA2RFNTAFNTBPGGT1BMAPT | |
| SCHEMBL2030047 | 0.83 | ESRRA (0.51) | MAPTHPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL1644299 | 0.82 | HTT (0.60) | MAPTHPGDARLMNAHTT | |
| SCHEMBL22867963 | 0.82 | AR (0.66) | FNTAFNTBPGGT1BARSMN1; SMN2 | |
| SCHEMBL5315872 | 0.79 | MAPT (0.67) | TBXA2RMAPTHPGDLMNAHTT | |
| SCHEMBL30676036 | 0.78 | ESRRA (0.54) | MAPTARLMNAHTTSMN1; SMN2 | |
| SCHEMBL26926649 | 0.78 | ESRRA (0.54) | MAPTARLMNAHTTSMN1; SMN2 | |
| SCHEMBL12595068 | 0.77 | AR (0.65) | MAPTARLMNAHTTALDH1A1 | |
| SCHEMBL4790993 | 0.77 | MAPT (0.71) | TBXA2RMAPTHPGDLMNAHTT | |
| SCHEMBL25386626 | 0.77 | NFE2L2 (0.55) | TBXA2RMAPTHPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |