Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601653 | 0.84 | TDP1 (0.48) | TACR3MAPTCYP1A2CYP3A4HPGD | |
| SCHEMBL8598420 | 0.82 | HTT (0.59) | MAPTCYP1A2HPGDKMT2AMEN1 | |
| SCHEMBL8564524 | 0.82 | MAPT (0.43) | TACR3MAPTHPGDKMT2AMEN1 | |
| SCHEMBL8563618 | 0.81 | ALDH1A1 (0.59) | MAPTHPGDKMT2AMEN1POLB | |
| SCHEMBL27444565 | 0.81 | MAPT (0.51) | MAPTHPGDKMT2AMEN1KDM4E | |
| SCHEMBL23202942 | 0.80 | KMT2A (0.55) | TACR3CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL30827859 | 0.80 | KMT2A (0.55) | TACR3CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL8567516 | 0.79 | AGTR1 (0.48) | MAPTHPGDKMT2APOLBKDM4E | |
| SCHEMBL8564716 | 0.78 | MAPT (0.47) | MAPTHPGDKMT2AMEN1KDM4E | |
| SCHEMBL8563079 | 0.78 | NCOA1 (0.54) | MAPTHPGDKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |