Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563618 | 0.88 | ALDH1A1 (0.59) | MAPTALDH1A1RXFP1KDM4ENPC1 | |
| SCHEMBL8564716 | 0.85 | MAPT (0.47) | MAPTALDH1A1KDM4EHTTNPC1 | |
| SCHEMBL8564524 | 0.80 | MAPT (0.43) | MAPTALDH1A1RXFP1KDM4EHTT | |
| SCHEMBL8559983 | 0.79 | MAPT (0.42) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL27444565 | 0.79 | MAPT (0.51) | MAPTALDH1A1KDM4EHTTNPC1 | |
| SCHEMBL8568306 | 0.78 | TACR3 (0.63) | MAPTKDM4EHTTSMN1; SMN2HPGD | |
| Quinoline SCHEMBL27446167 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL3956436 | 0.78 | NCF1 (0.51) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8566513 | 0.78 | CASP6 (0.44) | MAPTALDH1A1RXFP1KDM4EHTT | |
| SCHEMBL8567516 | 0.77 | AGTR1 (0.48) | MAPTALDH1A1KDM4ELMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |