Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27446167 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8564716 | 0.88 | MAPT (0.47) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8563079 | 0.88 | NCOA1 (0.54) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8564524 | 0.83 | MAPT (0.43) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8559983 | 0.82 | MAPT (0.42) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL27444565 | 0.82 | MAPT (0.51) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8568306 | 0.81 | TACR3 (0.63) | MAPTKDM4ESMN1; SMN2POLBMEN1 | |
| SCHEMBL8566513 | 0.80 | CASP6 (0.44) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL8567516 | 0.80 | AGTR1 (0.48) | ALDH1A1MAPTKDM4ELMNADHODH | |
| SCHEMBL8597050 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |