SCHEMBL8568402

SCHEMBL8568402

Nc1cc(C(=O)O)c(C(=O)O)nc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.42
KDM4E B2RXH2 9/20 0.41
KMT2A Q03164 6/20 0.41
GFER P55789 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
MAPT P10636 6/20 0.39
TDP1 Q9NUW8 5/20 0.39
MEN1 O00255 5/20 0.39
THRB P10828 4/20 0.39
RECQL P46063 2/20 0.39
BLM P54132 2/20 0.39
USP2 O75604 2/20 0.39
PKM P14618 2/20 0.39
MCL1 Q07820 2/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
ALDH1A1 P00352 6/20 0.38
CYP3A4 P08684 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM6B O15054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2807041 0.80 GABRP (0.47) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL7220645 0.78 GABRP (0.53) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL258457 0.77 ALDH1A1 (0.43) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL29110843 0.75 ALDH1A1 (0.41) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL30660932 0.75 ALDH1A1 (0.41) IDO1KDM4EKMT2AMAPTMEN1
SCHEMBL8566616 0.74 LMNA (0.42) KDM4ETDP1POLBALDH1A1CYP3A4
SCHEMBL8566611 0.74 LMNA (0.42) KDM4ETDP1POLBALDH1A1CYP3A4
SCHEMBL17111440 0.74 IDO1 (0.47) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL27912178 0.73 ALDH1A1 (0.47) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL17111431 0.73 IDO1 (0.46) IDO1KDM4EKMT2AGFERRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP claimed