Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566702 | 0.90 | RARB (0.47) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL8570958 | 0.84 | HIF1A (0.38) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL8568404 | 0.83 | IKBKB (0.35) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL8567961 | 0.83 | FAAH (0.47) | HIF1AEPAS1KDM4EEPHX2FAAH | |
| SCHEMBL8567726 | 0.83 | CNR2 (0.41) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL8568941 | 0.83 | CNR2 (0.39) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL8566045 | 0.82 | FAAH (0.41) | HIF1AEPAS1KDM4EMAPK1LMNA | |
| SCHEMBL8572650 | 0.82 | CNR2 (0.47) | LMNAFAAHCNR2CNR1MEN1 | |
| SCHEMBL8566872 | 0.82 | CNR2 (0.47) | LMNAFAAHCNR2CNR1MEN1 | |
| SCHEMBL8569219 | 0.82 | CNR2 (0.47) | LMNAFAAHCNR2CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |