Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569349 | 0.87 | ADAMTS4 (0.38) | ALDH1A1HPGD | |
| SCHEMBL8568591 | 0.86 | PTAFR (0.41) | ALDH1A1HPGDBMP1PTAFR | |
| SCHEMBL8563029 | 0.86 | PTAFR (0.41) | ALDH1A1HPGDBMP1PTAFR | |
| SCHEMBL8566997 | 0.80 | ADAMTS4 (0.37) | ALDH1A1HPGDMMP1 | |
| SCHEMBL8561481 | 0.78 | PTAFR (0.49) | ALDH1A1HPGDPTAFR | |
| SCHEMBL8565202 | 0.77 | MMP2 (0.34) | ALDH1A1HPGDMMP1 | |
| SCHEMBL8565588 | 0.77 | MMP2 (0.34) | ALDH1A1HPGDMMP1 | |
| SCHEMBL8563698 | 0.76 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8571542 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HPGDMMP1BMP1PTAFR | |
| SCHEMBL8570622 | 0.76 | PTAFR (0.35) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | claimed |
| EP-0605434-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-07-13 | — | — | EP | claimed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | claimed |
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | disclosed |
| US-5446032-A | Platelet activsating factor antagonist | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-08-29 | — | — | US | disclosed |
| EP-0605434-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |