⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001727 | 0.70 | — | — | |
| SCHEMBL622632 | 0.65 | — | — | |
| SCHEMBL31295070 | 0.64 | — | — | |
| SCHEMBL1009287 | 0.64 | — | — | |
| SCHEMBL11702945 | 0.64 | — | — | |
| SCHEMBL3407215 | 0.60 | ALDH1A1 (0.39) | — | |
| SCHEMBL29956303 | 0.60 | L3MBTL1 (0.32) | — | |
| SCHEMBL3922703 | 0.60 | APLNR (0.44) | — | |
| SCHEMBL20188976 | 0.60 | MAPT (0.32) | — | |
| SCHEMBL11368927 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | claimed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | claimed |
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |