Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568956 | 1.00 | MTNR1A (0.38) | MTNR1ASIGMAR1NUDT1BACE1NQO2 | |
| SCHEMBL8031506 | 0.93 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8575802 | 0.92 | CTSD (0.41) | SIGMAR1BACE1 | |
| SCHEMBL8521537 | 0.92 | CTSD (0.41) | SIGMAR1BACE1 | |
| SCHEMBL8521850 | 0.88 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1BESR1 | |
| SCHEMBL8569498 | 0.88 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1BESR1 | |
| Hydrochloric Acid SCHEMBL8604302 | 0.87 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1BESR1 | |
| Hydrochloric Acid SCHEMBL8604303 | 0.87 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1BESR1 | |
| SCHEMBL8035005 | 0.87 | SIGMAR1 (0.40) | SIGMAR1BACE1 | |
| SCHEMBL8033089 | 0.82 | SIGMAR1 (0.42) | MTNR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5780512-A | MELATONINERGIC | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |