Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521850 | 1.00 | MTNR1A (0.39) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| Hydrochloric Acid SCHEMBL8604303 | 0.98 | MTNR1A (0.39) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| Hydrochloric Acid SCHEMBL8604302 | 0.98 | MTNR1A (0.39) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| SCHEMBL8033089 | 0.93 | SIGMAR1 (0.42) | MTNR1ASIGMAR1DRD2 | |
| SCHEMBL8568951 | 0.88 | MTNR1A (0.38) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| SCHEMBL8568956 | 0.88 | MTNR1A (0.38) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| SCHEMBL8521537 | 0.86 | CTSD (0.41) | SIGMAR1DRD2 | |
| SCHEMBL8575802 | 0.86 | CTSD (0.41) | SIGMAR1DRD2 | |
| SCHEMBL8034996 | 0.83 | MTNR1A (0.37) | MTNR1ASIGMAR1MTNR1BNQO2ESR1 | |
| SCHEMBL8031506 | 0.82 | SIGMAR1 (0.41) | SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5780512-A | MELATONINERGIC | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |