Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597724 | 0.72 | REN (0.41) | RENCNR2ALDH1A1LMNAKMT2A | |
| SCHEMBL8569428 | 0.65 | CNR2 (0.39) | RENCNR2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3099150 | 0.62 | HPGD (0.50) | ALDH1A1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL27343657 | 0.61 | NPC1 (0.56) | ALDH1A1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28511075 | 0.61 | EGFR (0.47) | ALDH1A1LMNAHPGDAGTR1KDM4E | |
| SCHEMBL27249759 | 0.60 | MEN1 (0.72) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL15174796 | 0.60 | EZH2 (0.56) | ALDH1A1LMNAKMT2ASMN1; SMN2HPGD | |
| SCHEMBL367564 | 0.60 | HPGD (0.50) | ALDH1A1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL365591 | 0.60 | HPGD (0.49) | CNR2ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL13899448 | 0.59 | HTT (0.56) | KMT2ASMN1; SMN2MEN1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729469-B1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | UPJOHN CO (US) | 1998-09-23 | — | — | EP | claimed |