Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569428 | 0.83 | CNR2 (0.39) | RENHPGDKMT2ATACR1MEN1 | |
| SCHEMBL5335958 | 0.76 | TACR1 (0.58) | HPGDKMT2ATACR1LMNAALDH1A1 | |
| SCHEMBL9376187 | 0.73 | LCK (0.54) | — | |
| SCHEMBL8569427 | 0.72 | REN (0.40) | RENHPGDKMT2AMEN1GNE | |
| SCHEMBL3356849 | 0.67 | GABRA5 (0.50) | — | |
| SCHEMBL367564 | 0.67 | HPGD (0.50) | HPGDKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3099150 | 0.66 | HPGD (0.50) | HPGDKMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL365591 | 0.66 | HPGD (0.49) | HPGDKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL14463536 | 0.64 | SMN1; SMN2 (0.54) | HPGDKMT2ATACR1MEN1LMNA | |
| SCHEMBL22767743 | 0.63 | KMT2A (0.52) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729469-B1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | UPJOHN CO (US) | 1998-09-23 | — | — | EP | claimed |