Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365591 | 0.99 | HPGD (0.49) | HPGDPOLBRAB9AHTTTDP1 | |
| SCHEMBL366310 | 0.89 | ALDH1A1 (0.52) | HPGDPOLBRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL365544 | 0.89 | REN (0.53) | — | |
| SCHEMBL365014 | 0.82 | KDM4E (0.48) | HPGDPOLBHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL365565 | 0.81 | KMT2A (0.52) | HPGDHTTTDP1LMNAALDH1A1 | |
| SCHEMBL364594 | 0.81 | EGFR (0.44) | HPGDPOLBHTTLMNAALDH1A1 | |
| SCHEMBL367563 | 0.80 | KDM4E (0.52) | HPGDPOLBRAB9AHTTTDP1 | |
| SCHEMBL365590 | 0.79 | KDM4E (0.51) | HPGDPOLBRAB9AHTTTDP1 | |
| SCHEMBL364207 | 0.79 | EGFR (0.47) | HPGDRAB9AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL364969 | 0.77 | KDM4E (0.53) | HPGDPOLBHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |