Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567834 | 0.81 | POLB (0.48) | CYP1A2CYP3A4HTTCA1CA2 | |
| SCHEMBL8566243 | 0.81 | MGMT (0.46) | HTTMGMTCA1CA2CA7 | |
| SCHEMBL8566342 | 0.78 | ALDH1A1 (0.48) | TXNRD1GSRCYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL8601717 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HTTMGMTNPY1R | |
| SCHEMBL8567904 | 0.76 | CA2 (0.39) | CA1CA2CA7CA13CA5A | |
| SCHEMBL8563877 | 0.76 | TXNRD1 (0.63) | TXNRD1GSRCYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL2683501 | 0.75 | NSD2 (0.38) | ALDH1A1CYP3A4NPY1RRAB9AMEN1 | |
| SCHEMBL8596381 | 0.75 | TXNRD1 (0.49) | TXNRD1GSRALDH1A1CYP3A4HPGD | |
| SCHEMBL8567046 | 0.74 | HTT (0.47) | ALDH1A1CYP3A4MAPK1HPGDHTT | |
| SCHEMBL8562624 | 0.74 | TXNRD1 (0.50) | TXNRD1GSRCYP2D6ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |