Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683501 | 0.85 | NSD2 (0.38) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL8601717 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL5126783 | 0.77 | PKM (0.42) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL8569457 | 0.76 | TXNRD1 (0.49) | CA2CA1CA9CA7CA13 | |
| SCHEMBL3688848 | 0.76 | MAPT (0.47) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL8596381 | 0.75 | TXNRD1 (0.49) | KMT2AMEN1USP2NPY1RMAPT | |
| SCHEMBL8599491 | 0.74 | HIF1A (0.39) | CA2CA1CA12CA9CA14 | |
| SCHEMBL8627058 | 0.74 | CA12 (0.35) | CA2CA1CA12CA9CA7 | |
| SCHEMBL8600533 | 0.74 | TDP1 (0.38) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL18486948 | 0.74 | KMT2A (0.42) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |