Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568499 | 0.86 | POLB (0.46) | POLBMEN1KMT2AABCG2SMN1; SMN2 | |
| SCHEMBL8560474 | 0.86 | POLB (0.46) | POLBTDP1MEN1KMT2AABCG2 | |
| SCHEMBL8568264 | 0.83 | POLB (0.41) | POLBABCG2SMN1; SMN2RAB9ATSHR | |
| SCHEMBL8562154 | 0.82 | POLB (0.43) | POLBMEN1KMT2AABCG2SMN1; SMN2 | |
| SCHEMBL8560780 | 0.81 | GAA (0.54) | L3MBTL1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8566078 | 0.80 | PIN1 (0.45) | POLBTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL1033969 | 0.79 | POLB (0.51) | POLBTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL8599819 | 0.77 | PLA2G2A (0.44) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL8561101 | 0.77 | POLB (0.53) | POLBTDP1MEN1KMT2AABCG2 | |
| SCHEMBL8597641 | 0.76 | KDM4E (0.41) | POLBMEN1KMT2AABCG2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |