Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569505 | 0.83 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1CYP1A2TSHR | |
| SCHEMBL8560780 | 0.82 | GAA (0.54) | GAASMN1; SMN2ALDH1A1EGFRCYP1A2 | |
| SCHEMBL8566078 | 0.81 | PIN1 (0.45) | POLBPIN1GAAALDH1A1TSHR | |
| SCHEMBL8560474 | 0.79 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1CYP1A2TSHR | |
| SCHEMBL8568499 | 0.79 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1CYP1A2TSHR | |
| SCHEMBL8599819 | 0.79 | PLA2G2A (0.44) | POLBGAAALDH1A1CYP1A2HTT | |
| SCHEMBL1803483 | 0.77 | ALDH1A1 (0.46) | GAAALDH1A1HPGD | |
| SCHEMBL8562154 | 0.76 | POLB (0.43) | POLBPIN1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8570921 | 0.75 | NPC1 (0.40) | POLBGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8564023 | 0.75 | MAPT (0.44) | POLBGAASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |