Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407040 | 0.77 | MAPT (0.64) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL27447787 | 0.69 | AURKA (0.41) | LMNAGAAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL5929645 | 0.69 | FABP3 (0.47) | MEN1KMT2A | |
| SCHEMBL8405322 | 0.67 | MAPT (0.52) | GAAMAPTSMN1; SMN2TP53MAPK1 | |
| SCHEMBL11239612 | 0.66 | ATP4A (0.53) | — | |
| SCHEMBL2911555 | 0.64 | KCNH2 (0.53) | GAAPOLBALDH1A1MAPTTP53 | |
| SCHEMBL5425953 | 0.63 | LRRK2 (0.45) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL5425955 | 0.63 | LRRK2 (0.42) | LMNATSHRALDH1A1TP53MAPK1 | |
| SCHEMBL3325263 | 0.62 | LMNA (0.52) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL2219070 | 0.61 | SMN1; SMN2 (0.65) | LMNAMEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843677-A1 | 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003074-A1 | 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |