Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793659 | 0.87 | P2RX7 (0.47) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL366547 | 0.84 | P2RX7 (0.55) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL6584070 | 0.83 | P2RX7 (0.53) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL6584064 | 0.83 | P2RX7 (0.53) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL25518906 | 0.82 | GHSR (0.53) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL7072069 | 0.81 | P2RX7 (0.52) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL21063860 | 0.81 | CA1 (0.53) | GHSRP2RX7MAOAMAOB | |
| SCHEMBL406043 | 0.80 | MTNR1A (0.57) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL15478536 | 0.80 | MTNR1A (0.57) | GHSRP2RX7MTNR1AMTNR1BFAAH | |
| SCHEMBL6642213 | 0.80 | GHSR (0.69) | GHSRP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365976-B1 | GAMMA SECRETASE MODULATORS | MERCK SHARP & DOHME (US) | 2015-04-15 | — | — | EP | disclosed |
| US-7488752-B2 | nor-seco himbacine derivatives; thrombosis, anticoagulants, anticancer agents; antiinflammatory agents; anticholesterol agents; cardiovascular disorders; antiarrhythmia agents; antiischemic agents; strokes; antiarthritic agents | SCHERING CORPORATION (US) | 2009-02-10 | — | — | US | disclosed |
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |