Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567776 | 0.82 | KMT2A (0.43) | POLQTACR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8565707 | 0.82 | POLQ (0.52) | POLQTACR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8566845 | 0.81 | CD274 (0.53) | KMT2AMEN1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL8720333 | 0.80 | KMT2A (0.51) | POLQKMT2AMEN1SMN1; SMN2SLC6A2 | |
| SCHEMBL8572406 | 0.80 | POLQ (0.53) | POLQTACR1PTGDR2 | |
| SCHEMBL3424186 | 0.79 | PTGS1 (0.49) | KMT2APTGDR2PDCD1CD274 | |
| SCHEMBL2393653 | 0.77 | TACR1 (0.47) | POLQTACR1 | |
| SCHEMBL8570068 | 0.77 | TACR1 (0.60) | POLQTACR1KMT2APDCD1CD274 | |
| SCHEMBL12202180 | 0.73 | POLQ (0.57) | POLQKMT2ASMN1; SMN2 | |
| SCHEMBL21359666 | 0.72 | PDCD1 (0.55) | TACR1KMT2APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |