Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.60 |
| ▸ | POLQ | O75417 | 5/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567778 | 0.84 | TACR1 (0.54) | TACR1POLQALDH1A1PDCD1CD274 | |
| SCHEMBL8566848 | 0.84 | TACR1 (0.53) | TACR1POLQALDH1A1PDCD1CD274 | |
| SCHEMBL8565708 | 0.84 | TACR1 (0.60) | TACR1POLQGPBAR1PDCD1CD274 | |
| SCHEMBL8572409 | 0.81 | TACR1 (0.69) | TACR1POLQGPBAR1 | |
| SCHEMBL8570065 | 0.77 | POLQ (0.45) | TACR1POLQPDCD1CD274KMT2A | |
| SCHEMBL6871097 | 0.75 | TACR1 (1.00) | TACR1GPBAR1 | |
| SCHEMBL3424186 | 0.71 | PTGS1 (0.49) | PDCD1CD274KMT2A | |
| SCHEMBL8720338 | 0.71 | TACR1 (0.57) | TACR1ALDH1A1KMT2A | |
| SCHEMBL31443047 | 0.71 | TRPM8 (0.46) | POLQALDH1A1KMT2A | |
| SCHEMBL24252550 | 0.70 | HSD11B1 (0.40) | TACR1ALDH1A1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |