Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566845 | 0.84 | CD274 (0.53) | KMT2ANR4A2MEN1SMN1; SMN2CD274 | |
| SCHEMBL8720333 | 0.83 | KMT2A (0.51) | KMT2ANR4A2MEN1SMN1; SMN2CD274 | |
| SCHEMBL8570065 | 0.82 | POLQ (0.45) | KMT2ANR4A2MEN1SMN1; SMN2CD274 | |
| SCHEMBL8462696 | 0.78 | PDCD1 (0.46) | KMT2ALMNARAB9ACD274PDCD1 | |
| SCHEMBL9890721 | 0.78 | MLNR (0.47) | KMT2AMEN1LMNALTB4R2SLC6A4 | |
| SCHEMBL8565707 | 0.78 | POLQ (0.52) | KMT2AMEN1SMN1; SMN2CD274PDCD1 | |
| SCHEMBL11571880 | 0.77 | SUCNR1 (0.53) | KMT2ALMNARAB9ACD274PDCD1 | |
| SCHEMBL8567778 | 0.75 | TACR1 (0.54) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL8572406 | 0.75 | POLQ (0.53) | ALDH1A1TACR1POLQ | |
| SCHEMBL2393306 | 0.74 | ALDH1A1 (0.42) | LMNARAB9AALDH1A1MAPTPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |