Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL5606559 | 1.00 | NAPRT (0.43) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL2424842 | 0.90 | CA2 (0.53) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL28257184 | 0.90 | CA2 (0.53) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL28040883 | 0.88 | CA2 (0.50) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL3147614 | 0.84 | NAPRT (0.41) | NAPRTTSHRTDP1CA2 | |
| Pyridine SCHEMBL6671998 | 0.82 | NAPRT (0.39) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL9785253 | 0.80 | NAPRT (0.47) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL2255454 | 0.80 | NAPRT (0.47) | NAPRTTSHRTDP1CA2GRIN1 | |
| Pyridine SCHEMBL984983 | 0.79 | TSHR (0.53) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL407438 | 0.79 | NAPRT (0.60) | NAPRTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059445-C | Novel derivatives of erythromycin, their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-12-13 | — | — | CN | disclosed |
| US-5760233-A | CHEMICAL INTERMEDIATES FOR MAKING ERYTHROMYCINS ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5656607-A | Erythromycin derivatives | ROUSSEL UCLAF (FR) | 1997-08-12 | — | — | US | disclosed |
| CN-1126997-A | Novel erythromycin derivatives, method for preparing same and use thereof as drugs | ROUSSEL UCLAF (FR) | 1996-07-17 | — | — | CN | disclosed |