Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168606 | 0.93 | OPRL1 (0.52) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL29445321 | 0.93 | OPRL1 (0.52) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL6168165 | 0.86 | CHRM3 (0.49) | CHRM3CHRM2OPRL1ACHEBCHE | |
| SCHEMBL8569508 | 0.86 | MEN1 (0.53) | CHRM3CHRM2OPRL1ACHEBCHE | |
| SCHEMBL8565096 | 0.85 | CCR5 (0.48) | CHRM3CHRM2OPRL1ACHE | |
| SCHEMBL6167277 | 0.85 | CHRM3 (0.53) | CHRM3CHRM2OPRL1ACHEBCHE | |
| SCHEMBL8571012 | 0.85 | CHRM2 (0.49) | CHRM3CHRM2OPRL1ACHEDRD2 | |
| SCHEMBL8564439 | 0.85 | CHRM2 (0.55) | CHRM3CHRM2OPRL1OPRM1DRD2 | |
| SCHEMBL6164748 | 0.84 | OPRL1 (0.44) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8571871 | 0.84 | CHRM3 (0.54) | CHRM3CHRM2OPRL1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |