SCHEMBL8570404

SCHEMBL8570404

O=C(Nc1ccccc1)C(Cl)CCl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
ALDH1A1 P00352 4/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
GAA P10253 3/20 0.58
ATM Q13315 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
HTT P42858 2/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
HSP90AA1 P07900 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
GPR55 Q9Y2T6 2/20 0.54
POLB P06746 1/20 0.53
RXFP1 Q9HBX9 1/20 0.49
EPHX2 P34913 2/20 0.48
TP53 P04637 1/20 0.48
EPHX1 P07099 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11713273 0.86 SMN1; SMN2 (0.52) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL10716382 0.83 KMT2A (0.53) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL15228212 0.83 MAPT (0.56) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL6901453 0.83 MAPT (0.61) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL10692644 0.83 L3MBTL1 (0.57) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL25431603 0.81 MAPT (0.54) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL27709662 0.81 ALDH1A1 (0.54) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL8769265 0.80 MAPT (0.57) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL4296111 0.79 MAPT (0.85) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7555674 0.79 POLB (0.61) MAPTALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012827-A1 HERBICIDAL COMPOSITION OF PROPANIL, CYHALOFOP BUTYL, AND 2,4-D COROMANDEL INTERNATIONAL LIMITED (IN) 2023-02-09 WO disclosed
CN-108601350-A Herbicide combinations UPL欧洲有限公司 2018-09-28 CN disclosed
CN-108495554-A The appropriate salt of gram elder brother for safe pyroxsulam composition 美国陶氏益农公司 2018-09-04 CN disclosed
CN-108471751-A Herbicidal compositions comprising 4-amino-3-chloro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid, florasulam and pyroxsulam or derivatives thereof 美国陶氏益农公司 2018-08-31 CN disclosed
CN-1290835-C Novel tetrazole derivatives BAYER AGROCHEM KK (JP) 2006-12-20 CN disclosed
CN-1440394-A Novel tetrazole derivatives BAYER AGROCHEM KK (JP) 2003-09-03 CN disclosed
CN-1052002-C Ether derivatives of tetrahydropyran and tetrahydrofuran, process for their preparation and pharmaceutical compositions containing them ZENECA LTD (GB) 2000-05-03 CN disclosed
WO-1998006780-A1 STABILIZER ADDITIVE FOR AGCHEMICAL TANK MIX ISP INVESTMENTS INC. (US) 1998-02-19 WO disclosed
EP-0793416-A1 ADJUVANT COMPOSITION FOR AGRICULTURAL CHEMICALS AND METHOD FOR ENHANCING THE EFFICACY OF AGRICULTURAL CHEMICAL Kao Corporation (JP) 1997-09-10 EP disclosed
WO-1996016539-A1 ADJUVANT COMPOSITION FOR AGRICULTURAL CHEMICALS AND METHOD FOR ENHANCING THE EFFICACY OF AGRICULTURAL CHEMICAL KAO CORPORATION (JP) 1996-06-06 WO disclosed
WO-1990013536-A1 BIS-(PYRROLIDONYL ALKYLENE) BIGUANIDES GAF CHEMICALS CORPORATION (US) 1990-11-15 WO disclosed
CN-1036564-A Sulfanilamide (SN) and contain the weedkiller of sulfanilamide (SN) as activeconstituents MITSUBISHI CHEM IND (JP) 1989-10-25 CN disclosed
EP-0318253-A1 Iminophenylthiazolidines, process of preparation, and method of use ICI AMERICAS INC. (US) 1989-05-31 EP disclosed
EP-0226815-A2 A particle growth inhibitor Kao Corporation (JP) 1987-07-01 EP disclosed
CN-85103730-A The preparation of weedicide and using method 1987-03-25 CN disclosed
CN-85103820-A 2-nitro-5 (2 '-chloro-4 '-the phenylfluoroform phenoxy group)-phenylacetate, thioesters and acid amides preparation method, weedicide and eliminate the method for injurious weed 1986-11-05 CN disclosed
EP-0175278-A2 Optical isomer of triazolylpentenols, and their production and use as fungicide herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed
EP-0068295-B1 A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE A. Nattermann & Cie. GmbH (DE) 1985-08-28 EP disclosed
EP-0124992-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-11-14 EP disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed