Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570404 | 0.83 | MAPT (0.58) | GAARAB9AALDH1A1ATMNPC1 | |
| SCHEMBL12096453 | 0.76 | L3MBTL1 (0.68) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL11776619 | 0.76 | PDK1 (0.56) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL7745302 | 0.75 | KCNK3 (0.79) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL7644547 | 0.74 | PDK1 (0.58) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL11015498 | 0.73 | L3MBTL1 (0.64) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL11031257 | 0.73 | ALDH1A1 (0.71) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL7930578 | 0.73 | L3MBTL1 (0.72) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL14533438 | 0.72 | L3MBTL1 (0.70) | L3MBTL1GAARAB9ABLMALDH1A1 | |
| SCHEMBL29034583 | 0.72 | L3MBTL1 (0.75) | L3MBTL1GAARAB9ABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | disclosed |