Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779517 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL8571445 | 0.80 | ALDH1A1 (0.43) | RAB9AALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL10807610 | 0.80 | DPP8 (0.48) | RAB9AALDH1A1MAPTHTR2ACYP2C19 | |
| SCHEMBL8568639 | 0.78 | ALDH1A1 (0.44) | RAB9AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8385774 | 0.77 | RAB9A (0.62) | RAB9AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL23956955 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL15388876 | 0.77 | RAB9A (0.61) | RAB9AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL27675512 | 0.76 | RAB9A (0.61) | RAB9AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL12814849 | 0.76 | RAB9A (0.60) | RAB9AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL9654481 | 0.75 | RAB9A (0.56) | RAB9AALDH1A1MAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35865-E | Preparation of glutaric acid derivatives | PFIZER INC. (US) | 1998-07-28 | — | — | US | disclosed |
| US-5714628-A | CARBOXYLATION A CYCLOHEXANONES TO A CYCLOPENTANECARBOXYLIC ACIDS WITH HYDROGEN PEROXIDE | PFIZER, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0391673-B2 | Preparation of glutaric acid derivatives | PFIZER LTD (GB) | 1997-04-02 | — | — | EP | disclosed |
| US-5166406-A | Peroxidation of cyclohexanone derivatives | PFIZER INC. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0391673-A1 | Preparation of glutaric acid derivatives | Pfizer Limited (GB) | 1990-10-10 | — | — | EP | disclosed |